Siloxane Nanoprobes for Labeling and Dual Modality Functional Imaging of Neural Stem Cells
نویسندگان
چکیده
منابع مشابه
Dual-Modality, Dual-Functional Nanoprobes for Cellular and Molecular Imaging
An emerging need for evaluation of promising cellular therapies is a non-invasive method to image the movement and health of cells following transplantation. However, the use of a single modality to serve this purpose may not be advantageous as it may convey inaccurate or insufficient information. Multi-modal imaging strategies are becoming more popular for in vivo cellular and molecular imagin...
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Breast cancer (BC) is a serious disease to threat lives of women. Numerous studies have proved that BC originates from cancer stem cells (CSCs). But at present, no one approach can quickly and simply identify breast cancer stem cells (BCSCs) in solid tumor. Nanotechnology is probably able to realize this goal. But in study process, scientists find it seems that nanomaterials with one modality, ...
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Multimodality tumor-specific nanoprobes that incorporate two or more imaging functionalities are becoming an integral part of early detection, molecular diagnosis and post-therapy assessment of cancer (1,2). Magnetic resonance imaging (MRI) and optical imaging are two complementary imaging modalities that provide superb anatomical and functional imaging information, respectively. Here we report...
متن کاملDual-Modal Nanoprobes for Imaging of Mesenchymal Stem Cell Transplant by MRI and Fluorescence Imaging
OBJECTIVE To determine the feasibility of labeling human mesenchymal stem cells (hMSCs) with bifunctional nanoparticles and assessing their potential as imaging probes in the monitoring of hMSC transplantation. MATERIALS AND METHODS The T1 and T2 relaxivities of the nanoparticles (MNP@SiO(2)[RITC]-PEG) were measured at 1.5T and 3T magnetic resonance scanner. Using hMSCs and the nanoparticles,...
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ژورنال
عنوان ژورنال: Annals of Biomedical Engineering
سال: 2015
ISSN: 0090-6964,1573-9686
DOI: 10.1007/s10439-015-1514-1